Improving cost-effectiveness analysis of childhood vaccines

Project Details

To review how equity and budgetary considerations have been taken into account within the cost-effectiveness literature on childhood vaccines.


Assessing the cost-effectiveness of new vaccines has been a priority area of research in recent years, yet most cost-effectiveness analyses fail to adequately address the distributional dimensions and equity implications of incorporating new vaccines within national immunisation schedules. Furthermore, in addition to incremental cost-effectiveness ratios, information on the budgetary impact of new vaccines is also essential for policy-makers. This project aims to provide an improved understanding of the economic and distributional impacts of the changing profile of childhood vaccines over the next decade, and contribute to the discussion on financing for policies aimed at reducing inequalities and improving the health of marginalised populations.


Dr Natalie Carvalho


University of Melbourne

Research Publications

A. Boujaoud MA, Mirelman AJ, DALZIEL K, CARVALHO N. Accounting for equity considerations in cost-effectiveness analysis: a systematic review of rotavirus vaccine in low- and middle-income countries. Cost-effectiveness and Resource Allocation 2018; 16:18.

CARVAHLO N, Jit M, Cox S, Yoong J, and Hutubessy RCW. Capturing budget impact considerations within economic evaluations: A systematic review of economic evaluations of rotavirus vaccine in low- and middle-income countries and a proposed assessment framework. Pharmacoeconomics. 2017 Sep 13. doi: 10.1007/s40273-017-0569-2.

Research Group

Faculty Research Themes

Infection and Immunology, Child Health

School Research Themes

Data science, health metrics and disease modeling

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Centre for Health Policy

MDHS Research library
Explore by researcher, school, project or topic.