Colorectal Cancer

Research Overview

Although we understand the major factors that increase the risk of developing colorectal cancer and we know that screening for colorectal cancer reduces the number of new cases and deaths, fundamental questions remain:

  • How can we increase the effectiveness of colorectal cancer screening?
  • How can we target prevention to those most at risk?
  • What is the best way to medically manage people with a genetic predisposition?
  • What are the best treatments and most accurate prognoses for people who do get colorectal cancer?

We undertake a comprehensive approach to find the answers to these questions to reduce the burden of colorectal cancer.


Professor Mark Jenkins (unit head)

Dr Driss Ait Ouakrim

Maggie Angelakos

Dr Dan Buchanan

Dr Ghazaleh Dashti

Ellie Dillon

Louisa Flander

Samantha Fox

Dr Harindra Jayasekara

Grant Lee

Dr Robert Macinnis

Judi Maskiell

Dr Jeanette Reece

Dr Bryony Thomson

Dr Aung Ko Win


Our research programs are based in national and international collaborations that were initiated in 1997 with the formation of the Australasian Colorectal Cancer Registry. We are a principal partner in an international pregistry of tens of thousands of participants from thousands of families who have generously provided questionnaire data, blood samples, and access to tumour tissue for future research.


Our Unit's research funding builds on our National Health and Medical Research Council Centre for Research Excellence for Reducing the Burden of Colorectal Cancer, and the National Institutes of Health (USA) Colorectal Cancer Family Registry Cohort.