Ye Kyaw Aung

Precision Prevention of Subsequent Extracolonic Primary Cancers for Colorectal Cancer Survivors

Ye Kyaw Aung

Principal Supervisor’s name: A/Prof. Aung Ko Win

Co-supervisors’ names: Prof. Mark Jenkins, Prof. Nancy Baxter

Colorectal cancer survivors are at risk of developing subsequent primary cancer (SPC) in both primary colorectum and extracolonic organs, which is neither a recurrence nor spread of the original cancer. Currently, there is no way to determine which survivors are at the highest risk of SPC. My PhD will develop a risk prediction model for a SPC, by studying 7,500 people from the Colon Cancer Family Registry over 15 years and validate the model using an independent cohort of colorectal cancer survivors from the Melbourne Collaborative Cohort Study. This model will help clinicians determine which survivors are at the highest risk of subsequent primary cancer in the extracolonic organs, allowing for early detection measures.

Source of funding: Melbourne Research Scholarship (Fee offset), Graduate Research Studentship supported by the National Health and Medical Research Council (NHMRC) Investigator Grant (APP1194392)