Management of Chlamydia Cases in Australia (MoCCA)
Chlamydia trachomatis (‘chlamydia’) is the most commonly diagnosed bacterial sexually transmitted infection (STI) worldwide and can have serious complications - 17% of cases will lead to pelvic inflammatory disease (PID) equating to over 30,000 cases per year in Australia. The risk of PID increases up to 4 fold in women who become reinfected, with very high reinfection rates among women in Australia (22% per year); this highlights the importance of strategies to prevent reinfection. Chlamydia can also lead to ectopic pregnancy and tubal factor infertility.
In Australia, general practice is a critical sector for chlamydia control because over 80% of chlamydia cases are diagnosed in this setting. The Australian Chlamydia Control Effectiveness Pilot was the first trial to show that increasing chlamydia screening in general practice will not reduce the burden of chlamydia in the population and identified considerable gaps in chlamydia case management to prevent reinfection. In response to these findings, there is now considerable ongoing discussion internationally that chlamydia control policy must prioritise case management through effective partner notification to prevent reinfection, timely re-testing after treatment to detect re-infection earlier and improved detection of PID.
Australian researchers have been at the forefront of research to identify effective innovative interventions for partner notification, chlamydia retesting and PID management in sexual health/family planning clinics. What is needed now, is to translate these interventions into general practice where the majority of chlamydia infections are diagnosed and managed.
The aim of the project is to reduce the burden of chlamydia infection by scaling up an integrated model of chlamydia case management in general practice. The project objectives are, in Australian general practice, to:
- Develop and refine an integrated model of chlamydia case management for implementation.
- Evaluate the clinical uptake, impact and cost-effectiveness of the model.
- Develop an implementation plan for scaling up the model.
The project commenced in mid-2018 and is due for completion in 2023.
Professor Rebecca Guy (Kirby Institute)
Professor Christopher Fairley (Melbourne Sexual Health Centre)
A/Prof David Regan (Kirby Institute)
Prof Basil Donovan (Kirby Institute)
Dr Lara Roeske (RACGP)
A/Prof Marcus Chen (Melbourne Sexual Health Centre)
Prof Claudia Estcourt (Glasgow Caledonian University)
Dr David Hawkes (VCS Pathology)
Jacqueline Coombe, Research Officer
- New South Wales Ministry of Health
- Victorian Government Department of Health and Human Services
- Queensland Health
- North Western Melbourne Primary Health Network
- Central and Eastern Sydney Primary Health Network
- Family Planning Victoria
- Family Planning NSW
- True Relationships & Reproductive Health
- Victorian Cytology Service
- Sydney Sexual Health Centre
NHMRC Partnership Project (APP1150014)
This research project is available to PhD, Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
Faculty Research Themes
School Research Themes
For further information about this research, please contact the research group leader.
Department / Centre
Unit / Centre
MDHS Research library
Explore by researcher, school, project or topic.