The Arthroplasty Surgical Antibiotic Prophylaxi (ASAP) Study
Project Details
The demand for total joint replacement surgery will double over the next decade. Infection involving the surgical wound is a devastating complication of this surgery. Half of all infections are due to methicillin resistant Staphylococcus (such as MRSA) and Enterococcus. This multicentre randomised controlled trial aims to investigate whether the addition of vancomycin at the time of surgery reduces the incidence of surgical wound infections; is safe and is cost-effective.
Project Duration
2017-2021
Researchers
- A/Prof An Duy Tran (Project lead)
Research Publications
Peel, T., Astbury, S., Cheng, A. C., Paterson, D., Buising, K., Spelman, T., Tran-Duy, A., de Steiger, R. S., & Group, A. T. (2019). Multicentre randomised double-blind placebo controlled trial of combination vancomycin and cefazolin surgical antibiotic prophylaxis: the Australian surgical antibiotic prophylaxis (ASAP) trial. BMJ Open, 9(11), e033718. https://doi.org/10.1136/bmjopen-2019-033718
Research Group
Health Economics and Simulation Modelling for Chronic Disease UnitSchool Research Themes
Data science, health metrics and disease modeling
Key Contact
For further information about this research, please contact the research group leader.
Department / Centre
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