Trial Integration of Polygenic Scores for Common Cancers into Standard Clinical Care

Project Details

Polygenic scores (PGS) describe a large component of the distribution of risk for common cancers in the population. Some, including colorectal, breast, ovarian and prostate cancers, have been validated in large cohorts making them ready for translational studies. This project is a clinical trial investigating the use of PGS alongside existing genetic testing for cancer predisposition. An economic evaluation of the current approach to genetic assessment of cancer risk will be performed. This will then be compared to the use of PGS alongside existing genetic assessment of cancer risk.

Project Duration

2023–2027

Researchers

• A/Prof Ilias Goranitis (Project Lead)

Funding

MRFF Genomics Health Futures