CURE-NG: Exploring community and expert perceptions of the acceptability of research that involves infecting the participant's throat with Neisseria gonorrhoeae

• Louise Keogh

  Professor

  l.keogh@unimelb.edu.au
  
• Eloise Williams

  Dr

  Eloise.Williams@mh.org.au
  

Project Details

This study will use focus groups and interviews with community members, and interviews with experts and key stakeholders to explore the acceptability of the establishment of an oropharyngeal controlled human infection model in Victoria.

This study aims to:

• Explore the perceptions of community members, experts and key stakeholders regarding the development of an oropharyngeal controlled human infection model
• Determine the barriers and enablers to potential future participants taking part in an oropharyngeal controlled human infection model
• Determine community preferences regarding key features of oropharyngeal controlled human infection model clinical trial design.

Researchers

Professor Louise Keogh

Dr Jessica Moulton

Collaborators

This collaboration includes a subset of investigators from the larger MRFF grant:

Dr Eloise Williams, Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity and Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital

Professor Jane Hocking, Sexual Health Unit, Melbourne School of Population and Global Health

Funding

Medical Research Future Fund Grant number: 107483 | Funding period: 2022 – 2025

Research Publications

Williams E, Hocking JS, Fairley CK, et al. Rationale and Ethical Assessment of an Oropharyngeal Gonorrhea Controlled Human Infection Model. J Infect Dis. 2025:jiaf029. doi:10.1093/infdis/jiaf029