CEB PhD Confirmation Seminar - Optimising dynamic treatment regimens using sequential multiple assignment randomised trial data with missing data

Ms Jessica Xu, B-BMed, MBiostats

Supervisors: Prof Julie Simpson, Dr Robert Mahar, Dr Anurika De Silva and Prof Katherine Lee

Clinicians often face multi-stage and dynamic decisions when treating patients with either chronic or progressive medical conditions. Sequential multiple assignment randomised trials (SMARTs) are clinical studies that randomise patients to different treatments over time, which provides data that can be used to optimise dynamic treatment regimens. However, repeatedly randomising patients to treatments can lead to complicated patterns of missing data. This PhD project will develop and evaluate statistical methods to optimise dynamic treatment regimens using data from hypothetical SMART designs with problematic missing data.

Location: MSPGH, Seminar Rooms 302/303, L3, 207 Bouverie Street or via zoom https://unimelb.zoom.us/j/85239014667?pwd=OXY5MnYxUG1WN3lWSTk3Tkk4L0ZxQT09&from=addon, password:  117615