A literature review on the relationship between PROMIS-29 and EQ-5D

A recent literature review by Dr Tianxin Pan, Professor Nancy Devlin and  Dr  An  Duy Tran from Health Economics Unit and colleagues from University of Technology Sydney (UTS), Curtin University and University of Pittsburgh, has been published in the Quality of Life Research.

EQ-5D and PROMIS-29 are both concise, generic measures of patient-reported outcomes accompanied by preference weights that allow the estimation of quality-adjusted life years (QALYs). However, they differ in how they measure and value health. This literature review synthesised existing evidence on the relationship between PROMIS-29 and EQ-5D. It found only nine studies that investigated the relationship between these instruments, and highlighted that more research comparing PROMIS-29 and EQ-5D-5L is needed, including a comparison of the two instruments as descriptive systems, comparing the characteristics of the value set, and validation of the EQ-5D-5L mapping algorithm from PROMIS-29 domains particularly in patient groups.

Funding for this study was provided by the EuroQol Research Foundation for the project “Exploring the relationship between EQ-5D-5L and PROMIS-29” led by Professor Devlin and A/Prof Brendan Mulhern from UTS. In their ongoing work, the team compares the characteristics of all the theoretical values from value sets for each instrument, and assess the impact of differences in both the instruments’ measurement properties and value sets using patient data. These two studies have been presented at the 2020 EuroQol Group Scientific Plenary Meeting and 2021 EuroQol Academy meeting, respectively.