How Consistent is the Relationship between HbA1c Control and Modelled Outcomes for People with T2DM


A recent analysis by Xinyang Hua and Professor Philip Clarke from the Health Economics Unit has been published in the journal PharmacoEconomics. This study systematically reviewed cost-effectiveness studies using type 2 diabetes simulation models and found that there is a consistent relationship between treatment effect assumptions on HbA1c and simulated outcomes in terms of quality-adjusted life-years and life expectancy. This relationship can be used as a benchmark to identify studies deviating from others, and generate long-term effectiveness predictions when insufficient resources are available to use a simulation model.

This paper is available to download online.