Hazel Clothier

This PhD evaluates “SAEFVIC”, the Victorian AEFI surveillance system’s ability to detect and investigate emergent vaccine safety issues.

Adverse events following immunisation (AEFI): Optimising passive surveillance to improve immunisation safety in Victoria

Hazel Clothier

Principle supervisor: Melissa Russell
Co-supervisors: Jim Buttery and Heath Kelly

Vaccines are a cornerstone of public health saving millions of lives, however, adverse events following immunisation (AEFI) are a reality. Comprehensive post-licensure vaccine safety surveillance is therefore essential to ensure immunisations remain safe. This PhD evaluates “SAEFVIC”, the Victorian AEFI surveillance system’s ability to detect and investigate emergent vaccine safety issues and explores application of a disproportionality measure to improve signal detection, providing the evidence-base to optimise the system and demonstrate SAEFVIC as a leader in Australian AEFI surveillance.

PhD scholarship:  Australian Government for the Research Trainee Scholarship